Assisted reproductive technologies assist couples in achieving pregnancy, though implantation depends on successful embryonic hatching from the zona pellucida.
Laser Hatching

Laser-assisted hatching is a specialized laboratory procedure performed during an IVF cycle utilizing precision laser technology to create a small opening in the zona pellucida (outer shell) of the embryo to facilitate implantation.

When Is It Done?

Clinical indications for laser-assisted hatching include:

  • Advanced maternal age
  • Prior implantation failure in assisted reproduction
  • Utilization of cryopreserved-thawed embryos
  • Diminished ovarian reserve or elevated FSH

Procedural Details

Light Pulsing

Under high-magnification microscopy, a controlled infrared laser pulse is applied to a localized region of the zona pellucida to thin or open the outer layer.

Implantation

Selected embryos are subsequently transferred into the uterine cavity.